The purpose of this document is to promote research in traditional herbal medicine and facilitate the access and evaluation of the quality, safety and efficacy of traditional herbal medicines using acceptable clinical and laboratory methodology after observation. This document will assist Zambian researchers to standardize the methodology for laboratory and clinical evaluation of traditional herbal medicines. The document offers a framework by which all traditional health practitioners and other non-conventional health practitioners in the country can enter the screening process, which will lead to their medicines or products being prioritized for evaluation. This document is intended for use by health institutions conducting research, including agencies, companies, involved in the development of traditional medicines in the country such as traditional health practitioners, naturopathic practitioners, pharmacologists, pharmacists, professionals and individuals.